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CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma.
Miyake T, Ueda Y, Matsuzaki S, Miyatake T, Yoshino K, Fujita M, Nomura T, Enomoto T, Kimura T. Miyake T, et al. J Cancer Res Clin Oncol. 2011 Apr;137(4):715-22. doi: 10.1007/s00432-010-0930-8. Epub 2010 Jun 23. J Cancer Res Clin Oncol. 2011. PMID: 20571827
METHODS: Expression of CRABP1 protein was investigated by immunohistochemical analysis in 100 ovarian carcinomas of various histological sub-types, including serous and clear cell adenocarcinomas. ...Disease-free survival of the serous and clear cell adenocarcino …
METHODS: Expression of CRABP1 protein was investigated by immunohistochemical analysis in 100 ovarian carcinomas of various histologi …
CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension.
Celestino R, Nome T, Pestana A, Hoff AM, Gonçalves AP, Pereira L, Cavadas B, Eloy C, Bjøro T, Sobrinho-Simões M, Skotheim RI, Soares P. Celestino R, et al. BMC Cancer. 2018 Jan 10;18(1):68. doi: 10.1186/s12885-017-3948-3. BMC Cancer. 2018. PMID: 29321030 Free PMC article.
RESULTS: We identified 17 genes significantly differentially expressed between mFTC and wFTC. C1QL1, LCN2, CRABP1 and CILP were differentially expressed in DTC in comparison with normal thyroid tissues. LCN2 and CRABP1 were also differentially expressed in DTC when …
RESULTS: We identified 17 genes significantly differentially expressed between mFTC and wFTC. C1QL1, LCN2, CRABP1 and CILP were diffe …
Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.
Huang Y, de la Chapelle A, Pellegata NS. Huang Y, et al. Int J Cancer. 2003 May 10;104(6):735-44. doi: 10.1002/ijc.11006. Int J Cancer. 2003. PMID: 12640681 Free article.
To determine whether the underexpression might be due to promoter methylation, we used combined bisulfite restriction analysis and bisulfite sequencing to study 7 underexpressed genes. Loss of expression of MT1G and CRABP1 is accompanied by hypermethylation in the 5' regio …
To determine whether the underexpression might be due to promoter methylation, we used combined bisulfite restriction analysis and bisulfite …
Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases.
Napoli JL. Napoli JL. Pharmacol Ther. 2017 May;173:19-33. doi: 10.1016/j.pharmthera.2017.01.004. Epub 2017 Jan 27. Pharmacol Ther. 2017. PMID: 28132904 Free PMC article. Review.
Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and function. ...Altered BP expression affects retinoid function, for example, by impairing pancreas development resul …
Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and FABP5, shepherd the poorly aqueous soluble retinoids duri …
Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Han SW, Lee HJ, Bae JM, Cho NY, Lee KH, Kim TY, Oh DY, Im SA, Bang YJ, Jeong SY, Park KJ, Park JG, Kang GH, Kim TY. Han SW, et al. Int J Cancer. 2013 May 1;132(9):2209-16. doi: 10.1002/ijc.27888. Epub 2012 Oct 29. Int J Cancer. 2013. PMID: 23034738 Free article.
Stages II and III sporadic colorectal cancer patients who underwent curative resection followed by adjuvant FOLFOX were included. Eight CpG island loci (CACNA1G, CRABP1, IGF2, MLH1, NEUROG1, CDKN2A (p16), RUNX3 and SOCS1) and five microsatellite markers were examined. ...
Stages II and III sporadic colorectal cancer patients who underwent curative resection followed by adjuvant FOLFOX were included. Eight CpG …
Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma.
Lee HS, Kim BH, Cho NY, Yoo EJ, Choi M, Shin SH, Jang JJ, Suh KS, Kim YS, Kang GH. Lee HS, et al. Clin Cancer Res. 2009 Feb 1;15(3):812-20. doi: 10.1158/1078-0432.CCR-08-0266. Clin Cancer Res. 2009. PMID: 19188151
Hepatocellular carcinoma from female patients showed a higher number of methylated genes than hepatocellular carcinoma from male patients (11.2 versus 8.4, P = 0.006). The genes CRABP1 and SYK showed significant association between CpG island hypermethylation and patients' …
Hepatocellular carcinoma from female patients showed a higher number of methylated genes than hepatocellular carcinoma from male patients (1 …
Cimp-Positive Status is More Representative in Multiple Colorectal Cancers than in Unique Primary Colorectal Cancers.
Tapial S, Olmedillas-López S, Rueda D, Arriba M, García JL, Vivas A, Pérez J, Pena-Couso L, Olivera R, Rodríguez Y, García-Arranz M, García-Olmo D, González-Sarmiento R, Urioste M, Goel A, Perea J. Tapial S, et al. Sci Rep. 2019 Jul 19;9(1):10516. doi: 10.1038/s41598-019-47014-w. Sci Rep. 2019. PMID: 31324877 Free PMC article.
We analyzed CIMP status of 229 individuals with CRC using an eight-marker panel (CACNA1G, CDKN2A, CRABP1, IGF2, MLH1, NEUROG1, RUNX3 and SOCS1); CIMP-(+) tumors were defined as having 5 methylated markers. ...
We analyzed CIMP status of 229 individuals with CRC using an eight-marker panel (CACNA1G, CDKN2A, CRABP1, IGF2, MLH1, NEUROG1, RUNX3 …
Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids.
Tsai YJ, Wu SY, Huang HY, Ma DH, Wang NK, Hsiao CH, Cheng CY, Yeh LK. Tsai YJ, et al. BMC Ophthalmol. 2015 Oct 26;15:142. doi: 10.1186/s12886-015-0145-5. BMC Ophthalmol. 2015. PMID: 26503156 Free PMC article.
Immunohistochemical staining for beta-catenin, cellular retinoic acid binding protein 1 (CRABP1), cellular retinoic acid binding protein 2 (CRABP2), fatty acid-binding protein 5 (FABP5), retinoic acid receptors (RAR-alpha, -beta, -gamma), and retinoid X receptors (RXR-alph …
Immunohistochemical staining for beta-catenin, cellular retinoic acid binding protein 1 (CRABP1), cellular retinoic acid binding prot …
The molecular signature of endometriosis-associated endometrioid ovarian cancer differs significantly from endometriosis-independent endometrioid ovarian cancer.
Banz C, Ungethuem U, Kuban RJ, Diedrich K, Lengyel E, Hornung D. Banz C, et al. Fertil Steril. 2010 Sep;94(4):1212-1217. doi: 10.1016/j.fertnstert.2009.06.039. Epub 2009 Jul 30. Fertil Steril. 2010. PMID: 19643405 Free PMC article.
The second group contained the genes StAR, SPINT1, Keratin 8, FoxM1B, FOLR1, CRABP1, and Claudin 7. They were equally regulated in EAOC and OC but not in ovarian endometriosis and benign ovaries. ...
The second group contained the genes StAR, SPINT1, Keratin 8, FoxM1B, FOLR1, CRABP1, and Claudin 7. They were equally regulated in EA …
WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Kawasaki T, Ohnishi M, Suemoto Y, Kirkner GJ, Liu Z, Yamamoto H, Loda M, Fuchs CS, Ogino S. Kawasaki T, et al. Mod Pathol. 2008 Feb;21(2):150-8. doi: 10.1038/modpathol.3800996. Epub 2007 Dec 14. Mod Pathol. 2008. PMID: 18084250 Free article.
Utilizing 903 population-based colorectal cancers and real-time PCR (MethyLight), we quantified DNA methylation in WRN and eight other promoters (CACNA1G, CDKN2A, CRABP1, IGF2, MLH1, NEUROG1, RUNX3 and SOCS1) known to be specific for CIMP. ...
Utilizing 903 population-based colorectal cancers and real-time PCR (MethyLight), we quantified DNA methylation in WRN and eight other promo …
15 results